Medication-Related Osteonecrosis of the Jaws: Bisphosphonates, Denosumab, and New Agents (pdf)

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Medication-Related Osteonecrosis of the Jaws: Bisphosphonates, Denosumab, and New Agents (pdf)

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Medication-Related Osteonecrosis of the Jaws: Bisphosphonates, Denosumab, and New Agents (pdf)
Osteonecrosis of the jaws is a well-known side-effect of anti-resorptive therapy that predominantly occurs in patients suffering from malignant diseases and receiving intravenous administrations of nitrogen-containing bisphosphonates or --subcutaneous administrations of denosumab, a monoclonal antibody. Less frequently it may also be observed in patients with osteoporosis who are being treated with these anti-resorptive drugs.

This textbook provides detailed, up-to-date information on all aspects of medication-related osteonecrosis of the jaws, including clinical features, pathogenesis, treatment options, and preventive measures. It also explains safe prevention and treatment strategies for patients receiving anti-resorptive drugs who require extractions, implant insertions, and other dento-alveolar surgeries. This book will be of major interest for medical and dental students, dentists, and oral and maxillofacial surgeons as well as osteologists and oncologists.


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